Matheus Cunha was taken off injured early in Manchester United's game against Burnley in a potentially huge blow to Ruben Amorim's side.

Brazilian came off in first halfHe immediately signalled to be substitutedWill be a doubt for derby against Manchester CityFollow GOAL on WhatsApp! 🟢📱WHAT HAPPENED?

The Brazilian forward appeared to hurt a muscle as he attempted to chase a through ball in the first half of the Premier League game at Old Trafford. Cunha knew he had done some damage as he immediately signalled to the bench that he had to be substituted, before he then dropped to the floor.

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The injury completed a miserable week for Cunha, who missed a penalty in United's shootout defeat by Grimsby, their first ever loss to a fourth division side and one of their most humiliating results ever.

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Cunha was United's first signing of the summer, joining from Wolves for £62.5m. Although he is yet to score or get an assist he has thrilled fans in his first few matches, especially against Arsenal. But he is now a doubt for the derby against Manchester City on September 14 and United's next league fixture against Chelsea on September 21. He is almost certain to miss Brazil's next two World Cup qualifiers, at home to Chile and away to Bolivia.

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Cunha will be assessed by United's medical staff but he is already a doubt for the derby against Manchester City on September 14 and United's next league fixture against Chelsea on September 20.